A263 MICE CHALLENGED WITH DNBS FOUR DAYS AFTER INFECTION WITH THE RAT TAPEWORM HYMENOLEPIS DIMINUTA ARE PROTECTED FROM COLITIS
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چکیده
منابع مشابه
Thymus dependence of tapeworm (Hymenolepis diminuta) elimination from mice.
Although normal mice eliminated the lumen-dwelling intestinal cestode Hymenolepis diminuta by day 21 post-cysticercoid inoculation, congenitally thymus-deficient (nude) mice maintained their work burdens. Nude mice grafted with thymus glands or injected with thymus cells eliminated their worms.
متن کاملExtracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice.
Analysis of parasite-host interactions can reveal the intricacies of immunity and identify ways to modulate immunopathological reactions. We assessed the ability of a phosphate-buffered saline-soluble extract of adult Hymenolepis diminuta to suppress macrophage (human THP-1 cell line, murine peritoneal macrophages) activity in vitro and the impact of treating mice with this extract on colitis i...
متن کاملHuman infection with Hymenolepis diminuta: case report from Spain.
We report a case of Hymenolepis diminuta infection in a human. The patient was a 5-year-old girl referred to us through the onset of a cyanotic attack. Treatment with a single dose (10 mg/kg of body weight) of praziquantel was ineffective, but the parasite was eradicated after three treatment cycles with the same drug at dosages of 25 mg/kg/day for 5 days.
متن کاملInfection with Hymenolepis diminuta Is More Effective than Daily Corticosteroids in Blocking Chemically Induced Colitis in Mice
PURPOSE To compare infection with the tapeworm, Hymenolepis diminuta, with steroid (dexamethasone) administration in the inhibition of dinitrobenzene sulfonic acid- (DNBS-) induced colitis in mice. PROCEDURES Mice were treated with DNBS +/- infected with H. diminuta or treated with daily dexamethasone (2 mg/Kg, ip.) and were assessed 72 hours post-DNBS by the calculation of disease activity a...
متن کاملIn Vitro Anthelmintic Effects of Senna Occidentalis (l.) Link (leguminosae) on Rat Tapeworm Hymenolepis Diminuta
Objective: This study was conducted to evaluate the anthelmintic activity of ethanolic leaf extract of Senna occidentalis on rat tapeworm Hymenolepis diminuta. Methods: Adult H. diminuta worms were obtained from laboratory maintained infection in rats. Different concentrations of crude ethanolic leaf extracts of S. occidentalis were tested in vitro on H. diminuta and praziquantel (PZQ) was used...
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ژورنال
عنوان ژورنال: Journal of the Canadian Association of Gastroenterology
سال: 2020
ISSN: 2515-2084,2515-2092
DOI: 10.1093/jcag/gwz047.262